The humans of the Federation are the Ancients.

• Shuttles look a lot like puddlejumpers.
• The Federation is very widespread, has transporters and other technology on par with the Ancients.
• Vulcans->Asgard? Lack of genetic diversity after destruction of Vulcan, tech, logic.
• Federation founded by 4 races just like the Ancients/Asgard/Furlings/Nox alliance- humans, Vulcans, Andorians, Tellarites.