Patrick Jane on truth serum (or anything else that destroys his verbal inhibitions): most horrifying thing ever, or what?  Throughout the show we keep getting shown how he has a tendency towards saying things that he shouldn't, hitting where it hurts; I get the impression that he only holds off in regards to the team (as far as that goes, anyway) because a) he likes them and b) he's using them to get to Red John, but that doesn't mean he isn't gathering all sorts of information about them that would come spilling out in that kind of situation.  It would end VERY BADLY.  Or possibly everybody would be used enough to him that they could get over it.